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Symbol
Name
ID

Otof
otoferlin
MGI:1891247

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Absent brainstem auditory responses
Disease(s) Associated with OTOF	Absent brainstem auditory responses
autosomal recessive nonsyndromic deafness 9

Mouse Phenotypes		nervous system phenotype	abnormal cochlear hair cell stereociliary bundle morphology	abnormal cochlear inner hair cell morphology	abnormal inner hair cell synaptic ribbon morphology	abnormal cochlear inner hair cell physiology	decreased cochlear VIII nucleus size	abnormal cochlear nerve morphology	abnormal synaptic transmission	abnormal miniature excitatory postsynaptic currents	abnormal paired-pulse facilitation
Availability	Mouse Genotype	nervous system phenotype	abnormal cochlear hair cell stereociliary bundle morphology	abnormal cochlear inner hair cell morphology	abnormal inner hair cell synaptic ribbon morphology	abnormal cochlear inner hair cell physiology	decreased cochlear VIII nucleus size	abnormal cochlear nerve morphology	abnormal synaptic transmission	abnormal miniature excitatory postsynaptic currents	abnormal paired-pulse facilitation
	Otof^deaf5Jcs/Otof^deaf5Jcs
	Otof^pga/Otof^pga
	Otof^tm1.1Erei/Otof^tm1.1Erei	*
	Otof^tm1Ugds/Otof^tm1Ugds

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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